Researchers from the Faculty of Engineering are using artificial intelligence (AI) to study the dangers of ‘forever chemicals’ – persistent compounds found in everyday items like non-stick cookware, paint and dental floss.

These chemicals, known as PFAS (per- and polyfluoroalkyl substances), contain strong bonds that make them extremely hard to break down, causing them to build up in the environment, food and even our bodies. Exposure to forever chemicals has been linked to health issues, but scientists still don’t fully understand how they cause harm.

Dr Shan Yi from the Department of Chemical and Materials Engineering and her team will use AI to predict how PFAS molecules interact with proteins in the human body. By analysing protein structures, they aim to identify which ones bind to PFAS and what that could mean for our health.

The project has been awarded a Marsden Fund grant of $960,000 over three years.

This research will help experts better understand the health risks of forever chemicals, inform safer chemical management and identify safer alternatives, says Yi.

“We envision our research contributing to a safer, more sustainable future where all chemicals, both new and existing, are rigorously evaluated for potential risks before they enter the global market and our daily lives.”

Marsden Fund grants will support engineering researchers in projects exploring public health, climate adaptation and cultural heritage.